Yup - from what you described, sounds like cylinder #1 is dead.
Could be from no fuel / no fire / bad compression on that cylinder. Given what you've done so far - unlikely you got a faulty replacement injector or coil pack on #1 - though I'd still double check that it isn't something simple. Like a wonky o-ring on the injector or damaged wiring to the coil pack igniter. Could try swapping injectors and coil igniters - just to see if it stays with that cylinder. Verify that you are getting signals for spark and fuel - use a noid light for the injector or listen to the tell-tale ticking noise with an automotive stethoscope. Verify spark by externally grounding out the plug on a chassis ground, and visually see if the spark is there.
Would have to do a compression test to confirm, if it is a dead cylinder = looking at engine rebuild or engine swap.
Car will actually still run a fair amount of time on 3 cylinders - not well - but can still limp around. There was a poster on here that drove an incredible number of miles in this situation. Just have to pull fuel from that cylinder to prevent it from hydrolocking on fuel / dump raw fuel into the exhaust. Least get you far enough down the road to a point where you can fix it or replace the car outright.