I guess I'll chime in, since I have some experience in this as well. I have an 05 Elise, and I used it as a daily driver for about a year. Now I use it as more of an occasional daily driver and autocross car (SS and FP class, for those who autoX). I also know people with aftermarket supercharged and turbocharged Elises. Some are daily driven. Some are flogged on road racing tracks frequently.
I wouldn't have any concerns whether the supercharged version would mean much more wear and tear. Even the hardest driven cars have held up extremely well. Besides, that increased power is only utilized when the car is driven all out. For street driving, I wouldn't expect the car to be driven very hard (compared to its abilities). Keep in mind that Lotus knows many of their cars will be used at the track, so they're not going to use parts that can't hold up to heavy use.
I know someone competing with a 380HP Elise, and he is still using the stock transmission. His car uses the 2ZZ engine it came with, plus a large turbo, and had a lot of internal parts changed. His car is purpose built, lightened, has plenty of downforce, and will never be street legal again. It is scary fast! If the stock C64 can hold up to that, you shouldn't have to worry about it holding up to street use.
As far as the Elise vs. Exige question; The Exige is a bit heavier, but it produces a bit more downforce (I think it is around 120lbs more at 100mph). Unless it will be driven at the track, the decision really boils down to aesthetics and visibility through the rear window. The base Exige is a bit more difficult to see out the back. The Exige S, as Fish mentioned--forget it. For daily driving- where you have to do things like backing out of parking spaces, the Elise is much easier to deal with.
My advice for test drives - Get in and out of the car several times and make sure you'd/they'd be comfortable doing that frequently. Trust me- it will take a few tries to get it right.